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Symbol
Name
ID
Nkx6-1
NK6 homeobox 1
MGI:1206039
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
endocrine/exocrine gland phenotype
decreased pancreatic alpha cell number
decreased pancreatic beta cell number
increased pancreatic beta cell number
decreased pancreatic delta cell number
decreased pancreatic epsilon cell number
small pancreatic islets
decreased insulin secretion
Availability Mouse Genotype
Nkx6-1tm1Jlr/Nkx6-1tm1Jlr
Nkx6-1tm1Jlr/Nkx6-1tm1.2Msan
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Neurog3-cre)C1Able/0  (conditional)
*
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan/0
Tg(Gcg-cre)1Herr/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory